, allogeneic, and in vivo modalities. As the business evolves from clinical-stage operations to global commercial scale... strategies across autologous, allogeneic, and in vivo modalities, as well as across clinical and commercial supply models...
and in vivo studies across discovery and development stages Ensure all bioanalytical activities comply with global regulatory... understanding of drug discovery and development, including in vitro/in vivo pharmacology, ADME, PK/PD, and translational research...
for assessment of toxicity. Design and conduct in vitro and/or in vivo investigative and mechanistic studies in collaboration...
–vascular pathology, using integrated in vitro and in vivo models. Responsibilities · Study interactions between endothelial..., vasculature, and brain. · Utilize in vitro and in vivo models, including inflammatory and aging-related models. · Perform...
and in vivo modeling) to understand how breast cancers, particularly triple negative breast cancers, resist chemotherapy...
and in vivo proof-of-concept studies to evaluate novel extrahepatic, targeted siRNA delivery platforms across multiple pipeline...
/MS-based bioanalytical methods to drive in vivo PK, TK, and PK/PD analysis as well as in vitro stability characterization... understanding of in vivo PK, TK and PK/PD studies and corresponding bioanalytical assays as well as in vitro characterization assays...
to join a dynamic team and work on in vitro and in vivo biotransformation studies. In this role, you will leverage cutting-edge...
and in vivo proof-of-concept studies to evaluate siRNA library and characterize lead compounds for the target engagement...
, and multiplex assessment of multiple endpoints in a single sample. Spearhead the strategic planning and execution of ex vivo..., and oligo exposure assays specifically for tissues treated ex vivo with oligonucleotides or gene therapies, with emphasis...