programs from early discovery to the clinic. Responsibilities As the lead toxicologist, you will work within the DMPK... and Safety department to define safety and toxicology strategies for the portfolio from TID to the clinic. For targets...
discovery to the clinic. Responsibilities As the lead toxicologist, you will work within the DMPK and Safety department... to define safety and toxicology strategies for the portfolio from TID to the clinic. For targets, you will lead, perform...
plasticity in the visual cortex of mice, by utilizing virtual reality systems alongside in vivo whole cell recordings, plasticity... plasticity in behaving mice. This will involve developing novel plasticity paradigms using in vivo whole cell recordings...
findings into the clinic to benefit patients. There are around 100 postgraduate students at the Cambridge Institute, who play... models using in vivo CRISPR recombination. The aim of the project is to develop new therapeutic approaches for neoadjuvant...
and candidate drug targets with a high chance of relevance in the clinic. In this project, the student will compare results... between Drosophila cells, Drosophila in vivo models and human iPSC models of MND to gain new knowledge of the underlying mechanisms...
platform for in vivo cell engineering. The goal of our platform is to drive the delivery of complex genetic algorithms to cells... – either fixing them in the case of genetic disease or creating therapeutics in vivo for the treatment of autoimmune and cancer. Based...
. Scientists at CRUK CI aim to understand the fundamental biology of cancer and translate these findings into the clinic to benefit... transposon silencing is not yet fully understood. In your project you will exploit tissue culture as well as in vivo models...
clinic to benefit patients. There are around 100 postgraduate students at the Cambridge Institute, who play a vital... tissue culture as well as in vivo models, and carry out various biochemical, proteomic, imaging, genomics (including state...
from in vitro data and in vivo nonclinical studies to prediction of efficacy and safety in patients. Initiate and engage in... and PKPD, leading to quantitative translation to the clinic Build PKPD models to allow hypothesis testing and inform decision...
. Ensure translation from in vitro data and in vivo nonclinical studies to prediction of efficacy and safety in patients... knowledge of drug pharmacology and PKPD, leading to quantitative translation to the clinic Build PKPD models to allow...