and qPCR, western blotting, ELISA, cloning, gene perturbation or CRISPR-Cas9 approaches, and next-generation sequencing... with computational colleagues. Evaluate candidate therapeutics and pathway inhibitors in vitro and in vivo using appropriate controls...
, including DNA, RNA, mRNA, siRNA, CRISPR components, and other biologic payloads. Define and execute program strategies... therapeutics, or closely related drug delivery technologies for inhalation routes of exposure. Demonstrated expertise...
to interpret the pharmacology and biology of therapeutic proteins. Experience with other modalities such as siRNA, CRISPR-based... therapeutics, and cell therapies is highly beneficial. Proven ability to plan, coordinate, lead PK and/or PK/PD studies...
: nanoparticle engineering, targeted drug delivery, nucleic acid therapeutics, CRISPR technologies, radiotherapy, and related areas...
& Gene Delivery: nanoparticle engineering, targeted drug delivery, nucleic acid therapeutics, CRISPR technologies...
therapeutics for patients with serious or life-threatening diseases. With a highly experienced team of experts in immunology..., transient transfection, or CRISPR-mediated gene knockout. Experience in tumor biology or the tumor immune microenvironment...
into impactful biological discoveries that advance the next generation of therapeutics. We are seeking a creative and technically... for genetic perturbation applications, including gene overexpression and CRISPR-based genome engineering (e.g., knockout...
Description: We are looking for a thoughtful and driven scientist with hands-on experience in synthesis and analysis of bioconjugate therapeutics, excellent lab... chemistry applicable to production of bioconjugate therapeutics (e.g. high throughput mammalian expression systems, peptide...
has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting... immunoassays to enable the discovery and development of novel cancer therapeutics. The ideal candidate will be a strong...
therapies for neurological and hepatic disorders and assessing immune response to gene editing based therapeutics delivered... and mouse models and assesses efficacy of therapeutics. Assesses the functionality of engineered cells and evaluates...