Responsibilities: Design and lead innovative in vitro and in vivo studies to uncover mechanisms driving inflammatory and autoimmune...
across multiple therapeutic areas, aligning ADME objectives with project milestones. Design and interpret in vitro and in vivo ADME...
in vitro and in vivo ADME studies to inform lead optimization and candidate selection. Apply fit-for-purpose in silico models...
Proficiency with primary cell culture systems, ex vivo tissue models, and/or relevant in vivo disease models Strong analytical... Preferred Knowledge, Experience, and Skills: Expertise in ex vivo organoid models of lung and liver Expertise bridging...
and in vivo experiments Experience with ligand-based delivery, conjugates or receptor biology preferred. Demonstrated scientific...
of next-generation TCR-T cell therapies incorporating viral and non-viral ex vivo engineering as well as in vivo T cell therapy... aligned products. Job Responsibilities Develop effective in vivo T cell engineering strategies and delivery vectors. Lead...
understanding of in vitro and in vivo pharmacology, PK, and PD concepts in cancer biology is important. Knowledge/Skills...
, MA to lead in vivo model development and validation to advance novel immune-based therapies for CNS diseases. As a Sr. Scientist... drug discovery. Key responsibilities of the In Vivo Neuroimmunology Sr. Scientist include: Design, execute, and report...
: In this role, you will design and execute in vitro and ex vivo studies that advance priority oncology targets through the drug... and ex vivo assays (e.g., receptor occupancy, receptor density, PK/PD, tumor isolation, and blood cell analysis...
develops preclinical (ie. in vitro, ex vivo, and in vivo) translational models of various skin and/or hair disorders using... with 3D skin/hair models Understand and have experience with in vivo skin quality and hair growth models. Experience...