clone. These in silico predictions are then tested in vitro using iPSC and cell-line models. The group is a mixture of wet... wider Institute. About the Role: You will use CRISPR-Cas9 to generate genotypes of interest in human iPSC lines...
models of neurologic diseases, which will also involve the generation and culture of induced pluripotent stem cell (iPSC...
clone. These in silico predictions are then tested in vitro using iPSC and cell-line models. The group is a mixture of wet...
cell (iPSC)-derived cardiomyocytes and/or other cardiovascular cell types. Knowledge of advanced therapies, such as gene...
). You will be based in our dedicated iPSC facility, which focuses on genetic manipulation, lineage differentiation, and developing new.... You will be responsible for maintaining high-quality iPSC lines and carrying out a range of genetic and cellular experiments. This includes...
with PhD students and postdocs who study the feedback regulation mechanisms (interstasis) using iPSC-derived neurons. The role... will focus on cell biology techniques, in particular the generation, maintenance and characterisation of novel iPSC cells...
(MND) and Frontotemporal Dementia (FTD) using iPSC-derived neurons. The role will focus on cell biology techniques..., in particular the generation, maintenance and characterisation of novel iPSC cells, their differentiation into neurons, and cellular...
). We are seeking a Research Technician to help investigate the underlying mechanisms using both Drosophila and iPSC-derived neuron... to both Drosophila and iPSC-neuron research;therefore, experience in both areas is essential. Responsibilities will include Drosophila...
of inherited retinal degeneration using iPSC derived retinal organoids and animal models to explore potential therapies...
pipeline. Subject matter expertise in optimising human stem cell culture (ESC/iPSC), differentiation, and characterisation...