”, this research builds on the lab's previous work on cardiac iPSC models of Fabry disease (Stem Cell Reports, 2019), cardiac organoids... (The EMBO Journal, 2025) and their recent generation of five patient-derived iPSC lines (unpublished) in partnership...
will use phenotypic analysis of iPSC-derived dopamine neurons to understand mechanisms of action, contributing to translational...: Differentiating iPSC lines into dopamine neurons Performing optimized cellular, molecular, and metabolomic assays Analysing...
and deliver cytokine profiling datasets from PBMCs, primary cells, and iPSC-derived models, supporting biomarker discovery...
and advanced cell-culture systems such as organoids, iPSC, and/or air-liquid interface models. Computational skills for automated...
(ALS). You will perform large-scale phenotypic CRISPRn screens on human iPSC-derived microglia to identify modifiers of immune dysfunction... iPSC-derived microglia Develop and implement scalable assays to model immune responses and disease-relevant phenotypes...