clone. These in silico predictions are then tested in vitro using iPSC and cell-line models. The group is a mixture of wet... wider Institute. About the Role: You will use CRISPR-Cas9 to generate genotypes of interest in human iPSC lines...
of inherited retinal degeneration using iPSC derived retinal organoids and animal models to explore potential therapies...
with PhD students and postdocs who study the feedback regulation mechanisms (interstasis) using iPSC-derived neurons. The role... will focus on cell biology techniques, in particular the generation, maintenance and characterisation of novel iPSC cells...
(MND) and Frontotemporal Dementia (FTD) using iPSC-derived neurons. The role will focus on cell biology techniques..., in particular the generation, maintenance and characterisation of novel iPSC cells, their differentiation into neurons, and cellular...
pipeline. Subject matter expertise in optimising human stem cell culture (ESC/iPSC), differentiation, and characterisation...
. Experience with standard and advanced cell culture systems such as organoids, iPSC, and/or air/liquid interface models...
working experience with advanced cell culture techniques including organoid cultures, organ on a chip, iPSC cultures...
cell (iPSC)-derived cardiomyocytes and/or other cardiovascular cell types. Knowledge of advanced therapies, such as gene...
aneuploidy (MVA) society (https://mvasociety.org). The scientist will be based within the BRC induced pluripotent stem cell (iPSC...) facility, and their principal role will be to generate iPSC lines from rare disease patients. The position will be a 50:50...
models of neurologic diseases, which will also involve the generation and culture of induced pluripotent stem cell (iPSC...